I think you could do a whole semester on the history of adaptation of Frankenstein! For a few thoughts on the early 1931 film, see http://en.wikipedia.org/wiki/Frankenstein_(1931_film)#Difference_from_film_and_book
Note that the film was based more on a play than the original Shelley narrative. Fascinating stuff!
How WOULD you do a movie that is more faithful to the original source material?